Obesity or being overweight does not depend on body weight but on the amount of body fat, to be specific – the amount of adipose tissue.
Adipose tissue is located beneath the skin, around internal organs, in bone marrow and in breast tissue.
Continue readingAdipose deposits in different parts of the body have different biochemical profiles and adipose tissue have been recognized in recent years as a major endocrine organ, as it produces hormones such as leptin, resistin, which under normal conditions, provide feedback for hunger and satiety to the brain.
It provides insulation from heat and cold, protective padding around organs and hormone production. It is composed of adipocytes (roughly 80% of fat) and its main leptin purpose is to store energy in the form of lipids.
In severely obese persons excess adipose tissue is experienced as a mass hanging downward from the abdomen and is referred to as a panniculus which can complicate surgery. If a severely obese person quickly loses large amounts of fat (as in gastric bypass surgery), this panniculus will remain even if it has shrunken to its minimum abdominal fat volume and diameter, no amount of diet and exercise is able to eliminate it. It is a literal apron of the skin and the only option is surgical removal